REGENXBIO Initiates P-I/II Trial of RGX-202 for the Treatment of Duchenne Muscular Dystrophy
Shots:
- The company initiated the P-I/II dose evaluation & dose expansion trial (AFFINITY DUCHENNE) evaluating RGX-202 (IV) in patients with DMD
- The (AFFINITY DUCHENNE) trial EPs include safety, immunogenicity assessments, PD & PK measures of RGX-202, incl. microdystrophin protein levels in muscle, strength and functional assessments, incl. the NSAA & timed function tests
- Patient enrolment also undergoes in the (AFFINITY BEYOND) observational screening study & the primary objective is to evaluate the prevalence of AAV8 Abs for Duchenne in patients aged ~12yrs. RGX-202 is intended to support the targeted delivery & expression of genes throughout skeletal & heart muscle using NAV AAV8 vector
Ref: PRNewswire | Image: REGENXBIO
Click here to read the full press release
Neha is a Senior Editor at PharmaShots. She is passionate and very enthusiastic about recent updates and developments in the life sciences and pharma industry. She covers Biopharma, MedTech, and Digital health segments along with different reports at PharmaShots. She can be contacted at connect@pharmashots.com.